DSpace-CRIS 8
QUO VADIS, Lietuvos archeologijos mokslas?Publication [QUO VADIS, Lithuanian archaeological science?]research articleLietuvos archeologija, 2024, vol. 50, p. 13-26Archeologija kaip ir kiekvienas mokslas siekia atskleisti nežinoma pasiremdamas turimu įdirbiu ir reaguodamas į esamą situaciją. Straipsnis skirtas Lietuvos archeologijos mokslo esamos situacijos apibūdinimui ir matomų raidos tendencijų įvertinimui. Šiuo metu padėtis joje stabili, sistema susiformavusi ir funkcionuoja. Mokslinę tiriamąją veiklą vykdo trys institucijos, leidžiančios savo leidinius. Kadangi šiuolaikinė Lietuvos archeologija yra integrali pasaulio archeologijos mokslo dalis, esamą būklę tikslinga analizuoti lyginant su pasaulinėmis šio mokslo raidos tendencijomis. Tokiam palyginimui pasirinkti du aspektai: šeši pirmieji Colino Renfrew ir Paulo Bahno knygos Archaeology: Theories, Methods and Practice (Archeologija: teorija, metodai ir praktika) leidimai bei Europos archeologų asociacijos paskutinės, 30-os, konferencijos Romoje temų apžvalga. Pagal juos nustatyti tam tikri šiuolaikinės archeologijos mokslo bruožai. Lietuvos archeologijos mokslo raidos tendencijos įvardytos, remiantis trijų pagrindinių mokslo leidinių 2006–2023 m. straipsnių analize, atlikta vadovaujantis tais pačiais kriterijais. Palyginimas leido identifikuoti kai kuriuos Lietuvos archeologijos mokslo raidos savitumus, kurių analizė papildyta labiau vietine jos problemika.
1 - review articleRes Humanitariae, 2024, no. 32, p. 324-330
1 Kryžiaus slėpinio atsiskleidimas šventojo popiežiaus Jono Pauliaus II kalbose LietuvojePublication [Unfolding the mystery of the cross in the speeches by pope John Paul ii in Lithuania]research articleRes Humanitariae, 2024, no. 32, p. 307-323Šventasis popiežius Jonas Paulius II lankėsi Lietuvoje 1993 m. rugsėjo 4–8 d. Lankydamasis ir melsdamasis Kryžių kalne kalbėjo, jog čia yra tam, kad su tikinčiaisiais apmąstytų Kristaus kryžių ir jame slypinčius tiesos bei šviesos lobius. Kryžiuje atsiskleidžia „Dievo galybė ir Dievo išmintis“ (1 Kor 1, 24), jame yra Gerosios Naujienos esmė, leidžianti suprasti, kas yra Dievas ir kas yra žmogus. Šventasis Tėvas Jonas Paulius II, lankydamasis Lietuvoje, pasakė 15 oficialių kalbų ir pamokslų. Iš pasakytų kalbų atsiskleidžia, jog kryžius yra vienas iš ryškiausių akcentų Jono Pauliaus II žinioje Lietuvai. Iš 15-os kalbų 8-iose minimas „kryžius“. Kryžius minimas Šventojo Tėvo pamoksle šv. Mišiose Kryžių kalne – 37 kartus, Maldoje Antakalnio kapinėse prie Nepriklausomybės (1991) kankinių kapų – 16 kartų, Šventojo Tėvo kalboje Vilniaus Arkikatedroje Bazilikoje kunigams ir vienuoliams, vienuolėms ir klierikams – 7 kartus, Šventojo Tėvo kalboje jaunimui Kaune, Dariaus ir Girėno stadione – 3 kartus, Šventojo Tėvo pamoksle Žodžio liturgijoje Šiluvoje – 2 kartus, ir po 1 kartą Šventojo Tėvo pamoksle šv. Mišiose Vingio parke, Šventojo Tėvo kalboje inteligentijai Vilniaus universiteto Šv. Jonų bažnyčioje ir Šventojo Tėvo pamoksle šv. Mišiose Kaune, Santakoje. Iš viso „kryžius“ paminėtas 68 kartus. Šiame straipsnyje pristatomi kryžiaus slėpinio atskleidimo akcentai popiežiaus Jono Pauliaus II kalbose: kryžius – krikščioniškojo tikėjimo ženklas; kryžius – įprasminantis kančią; kryžius – stiprybės šaltinis; kryžius – teikiantis atpirkimą; kryžius – atveriantis amžinojo gyvenimo akiračius; kryžius – prisikėlimo ženklas.
1 Jono Pauliaus II dėmesys rengimosi santuokai procesui ir šeimų palaikymui: kultūriniai iššūkiai ir pagalbos būtinybėPublication [John Paul ii’s focus on the process of preparing for marriage and the support of families: cultural challenges and the need for help]research articleRes Humanitariae, 2024, no. 32, p. 290-306Jonas Paulius II (1920–2005) savo pontifikato metu ypatingą dėmesį skyrė šeimų klausimui ir netgi pelnė „šeimų popiežiaus“ titulą. Jo vadovavimo Romos Katalikų Bažnyčiai laikotarpiu (1978-2005) pasaulyje iškilo daugybė kultūrinių pokyčių, lėmusių mąstymo kaitą ir požiūrio į gyvenimo šeimoje formų kitimą. Šio straipsnio objektas – Jono Pauliaus II Apaštališkoji Adhortacija Familiaris Consortio ir joje sutelktas dėmesys rengimui santuokai bei įvairioms sielovadinėms iniciatyvoms ir pastoracinėms veikimo gairėms, nurodžiusioms ilgalaikius tikslus, siekiant teikti pagalbą šeimos gyvenimą besirenkantiems žmonėms. Jis suvokė rengimosi šeimos gyvenimui procesą kaip nuolatines trijų pakopų pastangas, leidžiančias subrendusiam asmeniui gyventi laimingą šeimos gyvenimą. Taip pat pristatė būtinybę skirti dėmesį šeimų palydėjimui po santuokos sudarymo. Jo didžiausias troškimas, kad ne tik krikščionys, bet ir „kiekvienas geros valios žmogus įsijungtų į šeimos vertybių gelbėjimą ir remtų jos poreikius“ (Jonas Paulius II 1981b, n. 86).
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- research articleLancet. London : The Lancet Publishing Group, 2003, vol. 362, iss. 9386., p. 782-788
Background. Treatment with angiotensin-converting-enzyme (ACE) inhibitors reduces the rate of cardiovascular events among patients with left-ventricular dysfunction and those at high risk of such events. We assessed whether the ACE inhibitor perindopril reduced cardiovascular risk in a low-risk population with stable coronary heart disease and no apparent heart failure. Methods We recruited patients from October, 1997, to June, 2000. 13 655 patients were registered with previous myocardial infarction (64%), angiographic evidence of coronary artery disease (61%), coronary revascularisation (55%), or a positive stress test only (5%). After a run-in period of 4 weeks, in which all patients received perindopril, 12 218 patients were randomly assigned perindopril 8 mg once daily (n=6110), or matching placebo (n=6108). The mean follow-up was 4.2 years, and the primary endpoint was cardiovascular death, myocardial infarction, or cardiac arrest. Analysis was by intention to treat...
56Scopus© Citations 2120 - research articleFronties in ecology and the environment. Hoboken : Wiley, 2010, vol. 8, iss. 3, p. 135-144
Recent comprehensive data provided through the DAISIE project (www.europe-aliens.org) have facilitated the development of the first pan-European assessment of the impacts of alien plants, vertebrates, and invertebrates – in terrestrial, freshwater, and marine environments – on ecosystem services. There are 1094 species with documented ecological impacts and 1347 with economic impacts. The two taxonomic groups with the most species causing impacts are terrestrial invertebrates and terrestrial plants. The North Sea is the maritime region that suffers the most impacts. Across taxa and regions, ecological and economic impacts are highly correlated. Terrestrial invertebrates create greater economic impacts than ecological impacts, while the reverse is true for terrestrial plants. Alien species from all taxonomic groups affect “supporting”, “provisioning”, “regulating”, and “cultural” services and interfere with human well-being. Terrestrial vertebrates are responsible for the greatest range of impacts, and these are widely distributed across Europe. Here, we present a review of the financial costs, as the first step toward calculating an estimate of the economic consequences of alien species in Europe.
13Scopus© Citations 932 Grasping at the routes of biological invasions: a framework for integrating pathways into policyPublication research articleJournal of applied ecology, 2008, vol. 45, no. 2, p. 403-4141 Pathways describe the processes that result in the introduction of alien species from one location to another. A framework is proposed to facilitate the comparative analysis of invasion pathways by a wide range of taxa in both terrestrial and aquatic ecosystems. Comparisons with a range of data helped identify existing gaps in current knowledge of pathways and highlight the limitations of existing legislation to manage introductions of alien species. The scheme aims for universality but uses the European Union as a case study for the regulatory perspectives. 2 Alien species may arrive and enter a new region through three broad mechanisms: importation of a commodity, arrival of a transport vector, and/or natural spread from a neighbouring region where the species is itself alien. These three mechanisms result in six principal pathways: release, escape, contaminant, stowaway, corridor and unaided. 3 Alien species transported as commodities may be introduced as a deliberate release or as an escape from captivity. Many species are not intentionally transported but arrive as a contaminant of a commodity, for example pathogens and pests. Stowaways are directly associated with human transport but arrive independently of a specific commodity, for example organisms transported in ballast water, cargo and airfreight. The corridor pathway highlights the role transport infrastructures play in the introduction of alien species. The unaided pathway describes situations where natural spread results in alien species arriving into a new region from a donor region where it is also alien. 4 Vertebrate pathways tend to be characterized as deliberate releases, invertebrates as contaminants and plants as escapes. Pathogenic micro-organisms and fungi are generally introduced as contaminants of their hosts. The corridor and unaided pathways are often ignored in pathway assessments but warrant further detailed consideration. 5 Synthesis and applications. Intentional releases and escapes should be straightforward to monitor and regulate but, in practice, developing legislation has proved difficult. New introductions continue to occur through contaminant, stowaway, corridor and unaided pathways. These pathways represent special challenges for management and legislation. The present framework should enable these trends to be monitored more clearly and hopefully lead to the development of appropriate regulations or codes of practice to stem the number of future introductions.
17 20Scopus© Citations 831 Disentangling the role of environmental and human pressures on biological invasions across EuropePublication research articleProceedings of the National Academy of Sciences of the United States of America. Washington : National Academy of Sciences, 2010, vol. 107, no. 27., p. 12157-12162The accelerating rates of international trade, travel, and transport in the latter half of the twentieth century have led to the progressive mixing of biota from across the world and the number of species introduced to new regions continues to increase. The importance of biogeographic, climatic, economic, and demographic factors as drivers of this trend is increasingly being realized but as yet there is no consensus regarding their relative importance. Whereas little may be done to mitigate the effects of geography and climate on invasions, a wider range of options may exist to moderate the impacts of economic and demographic drivers. Here we use the most recent data available from Europe to partition between macroecological, economic, and demographic variables the variation in alien species richness of bryophytes, fungi, vascular plants, terrestrial insects, aquatic invertebrates, fish, amphibians, reptiles, birds, and mammals. Only national wealth and human population density were statistically significant predictors in the majority of models when analyzed jointly with climate, geography, and land cover. The economic and demographic variables reflect the intensity of human activities and integrate the effect of factors that directly determine the outcome of invasion such as propagule pressure, pathways of introduction, eutrophication, and the intensity of anthropogenic disturbance. The strong influence of economic and demographic variables on the levels of invasion by alien species demonstrates that future solutions to the problem of biological invasions at a national scale lie in mitigating the negative environmental consequences of human activities that generate wealth and by promoting more sustainable population growth.
7Scopus© Citations 484 - research articleInternational journal of cancer, 2010-09-30, vol. vol. 127, no. iss. 9, p. 2209-2221
Malignant ascites is a common manifestation of advanced cancers, and treatment options are limited. The trifunctional antibody catumaxomab (anti-epithelial cell-adhesion molecule x anti-CD3) represents a targeted immunotherapy for the intraperitoneal (i.p.) treatment of malignant ascites secondary to epithelial cancers. In this phase II/III trial (EudraCT 2004-000723-15; NCT00836654), cancer patients (n = 258) with recurrent symptomatic malignant ascites resistant to conventional chemotherapy were randomized to paracentesis plus catumaxomab (catumaxomab) or paracentesis alone (control) and stratified by cancer type (129 ovarian and 129 nonovarian). Catumaxomab was administered as an i.p. infusion on Days 0, 3, 7 and 10 at doses of 10, 20, 50 and 150 mug, respectively. The primary efficacy endpoint was puncture-free survival. Secondary efficacy parameters included time to next paracentesis, ascites signs and symptoms and overall survival (OS). Puncture-free survival was significantly longer in the catumaxomab group (median 46 days) than the control group (median 11 days) (hazard ratio = 0.254: p < 0.0001) as was median time to next paracentesis (77 versus 13 days; p < 0.0001). In addition, catumaxomab patients had fewer signs and symptoms of ascites than control patients. OS showed a positive trend for the catumaxomab group and, in a prospectively planned analysis, was significantly prolonged in patients with gastric cancer (n = 66; 71 versus 44 days; p = 0.0313). Although adverse events associated with catumaxomab were frequent, they were manageable, generally reversible and mainly related to its immunologic mode of action. Catumaxomab showed a clear clinical benefit in patients with malignant ascites secondary to epithelial cancers, especially gastric cancer, with an acceptable safety profile.
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